This Cracked.com article claims that "goosebumps" used to refer to venereal sores:
Well, it's thought that "Goosey" is referencing an old slang term "goose" which was a nice but roundabout way of saying "voluptuous lady of the night" which in turn is a euphemism for "goddamn dirty hooker." In fact, the term "goose bumps" was originally slang for the red bumps caused by venereal diseases.
However, the more respectable etymology source Online Etymology Dictionary disagrees with this etymology:
also goose-bumps, "peculiar tingling of the skin produced by cold, fear, etc.; the sensation described as 'cold water down the back'" [Farmer], 1859, from goose (n.) + bump (n.). So called because the rough condition of the skin during the sensation resembles the skin of a plucked goose. Earlier in the same sense was goose-flesh (1803) and goose-skin (1761; as goose's skin 1744), and earlier still hen-flesh (early 15c.), translating Latin caro gallinacia.
Is there any evidence that the term "goosebumps" was ever used to refer to venereal sores?