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According to a study published in 1994 entitled "Serum TSH variability in normal individuals: the influence of time of sample collection" by Scobbo et al., there were significant differences between late-morning non-fasting TSH and early-morning fasting TSH tests: The late morning non-fasting TSH tests declined in 97 of 100 subjects by an average of 26.39%...


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Your question asks if there are any health benefits from intermittent fasting, preferably on humans vs mice. There is a very old 1957 Spanish study which was re-examined by JB Johnson in 2006 [1] where subjects in a nursing home alternately consumed either 56% or 144% of their daily caloric requirement over 3 years. There was a highly significant ...


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As for "increasing immune system", there may actually be some truth in that: Here, we show that prolonged fasting reduces circulating IGF-1 levels and PKA activity in various cell populations, leading to signal transduction changes in long-term hematopoietic stem cells (LT-HSCs) and niche cells that promote stress resistance, self-renewal, and lineage-...


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TL;DR: There is evidence both that 5:2 intermittent fasting diet increases activation of SIRT1, and that this gene allows for various health benefits, including fat regulation, insulin reduction (anti diabetic) and some anti-ageing properties. N.B: I limited the answer strictly to the scope of the health benefits as found in the OP's claim (specifically fat ...


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