6 votes
Accepted

Are there approved drugs where it's unknown how they work?

According to the FDA the question they want to answer at a new drug approval is: "Does this drug work for the proposed use?" To answer that question the FDA requires the drug company to submit ...
  • 32.5k
5 votes

Can up to 70% of scientific studies not be reproduced?

Yes, and the problem exists across many areas of science The problem of reproducibility is attracting a lot more attention. A recent Nature News Feature discusses the possible causes of bad results ...
  • 54.9k
5 votes

Are there approved drugs where it's unknown how they work?

Yes, it's known that some drugs work, but how they work is unknown. For example, acetaminophen (a.k.a. paracetemol). MedScape explains: The exact mechanism by which acetaminophen produces its ...
1 vote

Are there approved drugs where it's unknown how they work?

You don't have to look far to find examples of major classes of drug where we don't have a good knowledge of how they work. One of the earliest "modern" medical advances was anaesthetics, first used ...
  • 54.9k

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