In refuting an Indonesian Islamic council finding to the contrary,
AstraZeneca Indonesia director Rizman Abudaeri said in a statement: “At all stages of the production process, this virus vector vaccine does not use nor come in contact with pork-derived products or other animal products.”
I find the last bit of that statement somewhat hard to believe because e.g. the FDA noted in 2018 that:
Although synthetic media have been developed for growth of many medically important microorganisms, some still require additional nutrients which are easily provided by animal-derived products such as serum and blood. Viral vaccines are produced in living cells, which, similarly, require the addition of complex growth media components, such as fetal calf serum. [...] Cow components are often used simply because cows are very large animals, commonly used for food, and thus much material is available. Animal-derived products used in vaccine manufacture can include amino acids, glycerol, detergents, gelatin, enzymes and blood. Cow milk is a source of amino acids, and sugars such as galactose. Cow tallow derivatives used in vaccine manufacture include glycerol. Gelatin and some amino acids come from cow bones. Cow skeletal muscle is used to prepare broths used in certain complex media. Many difficult to grow microorganisms and the cells that are used to propagate viruses require the addition of serum from blood to the growth media.
So, is there more info available on how AZ grows their vaccine to support that summary statement that it doesn't come in contact with any animal products (unlike quite a few similar virus-vectored vaccines)?
After a bit more searching, it seems AZ uses HEK293 cells to grow their adenovirus... but according to a 2013 paper a way to grow these cells involved two products that are animal-free according to their manufacturers (SFMTransFx-293 and GlutaMAX) but also 5% v/v "FBS", which almost certainly means fetal bovine serum, in this context. Another paper substitutes those first two substances with DMEM, but still uses 10% FBS. This doesn't excluded that may also grow without FBS or in some other process though.