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Excess cortisol can damage the hippocampus, and we also know that stress can reduce the length of telomeres, which can lead to a shortened lifespan.

But does stress accelerate aging in other ways too, like accelerate skin wrinkling?

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    I think we need to focus the question. Obviously a stressed 50-year old is still 50 years old, so the title is misleading. The assumed knowledge is rather advanced - some references would help. But mostly, let's find a single notable claim we can address here, or the question is too broad.
    – Oddthinking
    Apr 30, 2014 at 1:33
  • I added some references and narrowed down a bit the question on a suggested edit. I hope it holds the original meaning and still gets more adequate to the site.
    – T. Sar
    Nov 27, 2015 at 10:32

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