This morning, I stumbled across a realfarmacy article which poses the question [Note: the linked page breaks in Chrome but worked in Firefox]:
Why is there such a strong emphasis on the development of wheat products all over the world when there are so many adverse and crippling effects such as neurological impairment, dementia, heart disease, cataracts, diabetes, arthritis and visceral fat accumulation, not to mention the full range of intolerances and bloating now experienced by millions of people? [Emphasis mine]
It goes on to provide rationale  such as the following for its claims that wheat is bad for people:
100% whole wheat products are based on modern wheat strains created by irradiation of wheat seeds and embryos with chemicals, gamma rays, and high-dose X-rays to induce mutations.
More specific explanations are:
Each grain of wheat contains about one microgram of Wheat Germ Agglutinin (WGA). Even in small quantities, WGA can have profoundly adverse effects. It may be pro-inflammatory, immunotoxic, cardiotoxic … and neurotoxic.
Dr William Davis has documented several hundred clinical studies on the adverse effects of wheat. These are studies that document the neurologic impairments unique to wheat, including cerebellar ataxia and dementia; heart disease; visceral fat accumulation and all its attendant health consequences; the process of glycation via amylopectin A of wheat that leads to cataracts, diabetes, and arthritis; among others.
Due to the unique properties of amylopectin A, two slices of whole wheat bread increase blood sugar higher than many candy bars. High blood glucose leads to the process of glycation that, in turn, causes arthritis (cartilage glycation), cataracts (lens protein glycation), diabetes (glycotoxicity of pancreatic beta cells), hepatic de novo lipogenesis that increases triglycerides and, thereby, increases expression of atherogenic (heart disease-causing) small LDL particles, leading to heart attacks. Repetitive high blood sugars that develop from a grain-rich diet are, in my view, very destructive and lead to weight gain (specifically visceral fat), insulin resistance, leptin resistance (leading to obesity), and many of the health struggles that many now experience.
And, when discussing people with "wheat related" health issues, a doctor claims
"...Once we remove wheat from their diets, most of their symptoms disappear within three to six months"
This isn't the first time I've heard such claims. In fact, a quick search for "Is wheat toxic" brings up a number of supporting results. I can't say that I read them all, but from the summaries, it seems that they all have doctors making statements about how wheat is, in effect, poisonous.
While it all sounds more like correlation than causality (100% of people who drink water die!), I was wondering if there is a grain of truth to the article. Is there something in wheat (even 100% whole wheat products) that makes it innately "bad" for human consumption? The second part is whether or not this bad stuff can legitimately be considered a cause for many health issues?