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There seem to be many people that claim grapefruit, in one form or another, helps dieters with weight loss.

Is there any good academically-rigorous evidence to support any of these claims?

Some of the claims:

People who ate half of a grapefruit before each meal (without making any other dietary changes) shed an average of three and a half pounds over 12 weeks, found a study from the Nutrition and Metabolic Research Center at Scripps Clinic in La Jolla, California."

Source: http://www.health.com/health/gallery/0,,20564855_4,00.html

The fruit's compounds aid in fat burning and stabilizing blood-sugar and insulin levels,' says Christine Gerbstadt, MD, author of Doctor's Detox Diet.

Source: http://www.health.com/health/gallery/0,,20564855_4,00.html

Further evidence of notability is the 'Grapefruit Diet', which Wikipedia describes as a fad diet.

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    This would appear to be the referenced study: online.liebertpub.com/doi/abs/10.1089/… – Oddthinking Jul 22 '12 at 16:13
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    According to this abstract, similar weight loss resulted from either water or grapefruit juice prior to meals which leads to a conclusion that "a low energy dense dietary preload in a caloric restricted diet is a highly effective weight loss strategy." However, those who drank grapefruit juice also "experienced significantly greater benefits in lipid profiles". ncbi.nlm.nih.gov/pmc/articles/PMC3039556 – John R Jul 22 '12 at 17:13
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    Maybe I'm not familiar with the protocol here - but what is the question being asked, exactly? – Mark Beadles Jul 22 '12 at 17:31
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    Mark, There seems to be many people (as evidenced by my references) that claim grapefruit,in one form or another, helps dieters with weight loss. Is there any good academically-rigorous evidence to support any of these claims? – John R Jul 22 '12 at 17:58
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    @John R: I added it to the main question body to make it more clear. – nico Jul 22 '12 at 18:01

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